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ICSI — Intracytoplasmic Sperm Injection — is one of the most significant advances in fertility medicine, offering hope to couples where male factor infertility has been the primary barrier to conception. At Sudha Fertility Centre in Hyderabad, our skilled embryologists perform ICSI with precision using state-of-the-art micromanipulation equipment, achieving fertilisation rates of 80–85% per cycle — among the best in Hyderabad. Whether you are dealing with low sperm count, poor motility, abnormal morphology, or azoospermia, ICSI at Sudha can give you the best possible chance of achieving a successful pregnancy.
ICSI is an advanced form of IVF in which a single, carefully selected healthy sperm is injected directly into the centre of a mature egg using a highly specialised microinjection needle. This bypasses the natural fertilisation process entirely, making it the most effective treatment when sperm are unable to penetrate the egg on their own. The resulting embryo is then cultured in our laboratory and transferred to the uterus, exactly as in a standard IVF cycle.
| Factor | IVF | ICSI |
|---|---|---|
| Fertilisation Method | Sperm and egg placed together in a dish — natural fertilisation | Single sperm injected directly into egg by embryologist |
| Best For | Couples without significant male factor infertility | Low sperm count, poor motility, azoospermia, failed IVF |
| Fertilisation Rate | 50–60% of eggs typically fertilise | 80–85% of eggs typically fertilise |
| Lab Complexity | Standard embryology | Requires micromanipulation equipment and specialist embryologist |
| Cost | Lower add-on cost | Slightly higher — recommended when male factor infertility is present |
| Embryo Quality | Comparable when sperm is healthy | Comparable — ICSI does not reduce embryo quality |
The IUI procedure at Sudha Fertility Centre Hyderabad is a simple, 4-step process completed over one menstrual cycle:
| ICSI Patient Profile | Fertilisation Rate | Clinical Pregnancy Rate |
|---|---|---|
| Women under 35, male factor infertility | 80–85% | Up to 85% per transfer |
| Women 35–37, ICSI with normal female factor | 80–85% | 60–70% per transfer |
| Women 38–40, ICSI | 75–80% | 45–55% per transfer |
| Azoospermia — TESE/PESA + ICSI | 70–80% of retrieved sperm | 50–65% per transfer |
| Frozen donor sperm + ICSI | 75–80% | Comparable to fresh sperm |
| ICSI after previous failed IVF | 80–85% | Depends on reason for prior failure |
For men diagnosed with azoospermia — the complete absence of sperm in the ejaculate — Sudha Fertility Centre Hyderabad offers surgical sperm retrieval techniques coordinated with ICSI on the same day:
Dr. S. Pradeepa — DGO, DNB(OG), MNAMS, ART, FICOG, Vice President of Sudha Fertility Centre. Dr. Pradeepa brings international-standard expertise in advanced ART and male factor infertility management. A member of ASRM, ESHRE, ISAR, FOGSI, and Faculty of the International Federation of Fertility Societies, she provides senior clinical guidance for all complex ICSI cases at our Hyderabad centre.
Dr. V. Pranitha Reshmi — MBBS, DGO, DNB, ICOG, FMAS. Dr. Pranitha is a Fertility Consultant at our Banjara Hills centre with 12 years of clinical experience in reproductive care, including IVF, ICSI, IUI, and minimally invasive procedures. She is known across Hyderabad for her empathetic, transparent approach to patient care.
Male factor infertility affects 1 in 3 couples seeking fertility treatment. ICSI at Sudha Fertility Centre Hyderabad has helped hundreds of men with even the most challenging sperm conditions become fathers. Call +91 76-7007-6006 or book your FREE consultation online at our Banjara Hills centre.
